Transgender Americans experience stigma and systemic inequality in many aspects of their lives, including education, work and health-care access, a wide-ranging Washington Post-KFF poll finds.

Many have been harassed or verbally abused. They’ve been kicked out of their homes, denied health care and accosted in bathrooms. A quarter have been physically attacked, and about 1 in 5 have been fired or lost out on a promotion because of their gender identity. They are more than twice as likely as the population at large to have experienced serious mental health struggles such as depression.